Jan Tack Selected Research

Motilin

1/2021	Gastric emptying of solutions containing the natural sweetener erythritol and effects on gut hormone secretion in humans: A pilot dose-ranging study.
1/2016	The pharmacodynamics, safety and pharmacokinetics of single doses of the motilin agonist, camicinal, in type 1 diabetes mellitus with slow gastric emptying.
1/2010	Colitis affects the smooth muscle and neural response to motilin in the rabbit antrum.

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Jan Tack Research Topics

Disease

45	Dyspepsia (Indigestion) 06/2022 - 02/2004
35	Constipation 10/2022 - 08/2002
24	Gastroesophageal Reflux (GERD) 01/2022 - 10/2002
22	Irritable Bowel Syndrome (Syndrome, Irritable Bowel) 01/2022 - 08/2002
20	Gastroparesis 11/2022 - 05/2004
19	Hypersensitivity (Allergy) 01/2022 - 08/2002
15	Pain (Aches) 01/2022 - 04/2010
14	Abdominal Pain (Pain, Abdominal) 01/2021 - 08/2002
12	Esophageal Achalasia (Megaesophagus) 01/2022 - 01/2010
12	Inflammation (Inflammations) 01/2021 - 01/2010
11	Opioid-Induced Constipation 02/2022 - 01/2014
11	Diarrhea 01/2021 - 01/2007
10	Nausea 01/2022 - 05/2004
8	Gastrointestinal Diseases (Functional Gastrointestinal Disorders) 12/2021 - 04/2006
7	Weight Loss (Weight Reduction) 01/2021 - 09/2009
7	Vomiting 01/2021 - 05/2004
6	Deglutition Disorders (Dysphagia) 01/2022 - 09/2013
6	Dumping Syndrome (Syndrome, Dumping) 01/2021 - 04/2009
6	Heartburn (Pyrosis) 01/2020 - 09/2007
5	Neoplasms (Cancer) 02/2022 - 01/2007
5	Obesity 01/2022 - 01/2018
5	Infections 10/2020 - 12/2005
5	Esophagitis 06/2010 - 08/2004
4	Cancer Pain 02/2022 - 10/2015
4	COVID-19 01/2022 - 09/2020
3	Headache (Headaches) 01/2019 - 02/2005
3	Body Weight (Weight, Body) 03/2015 - 01/2014
2	Chronic Pain 01/2022 - 10/2018
2	Critical Illness (Critically Ill) 01/2021 - 11/2011
2	Diffuse Esophageal Spasm (Esophageal Spasm) 01/2020 - 09/2013
2	Esophageal Motility Disorders (Nutcracker Esophagus) 01/2020 - 09/2013
2	Eosinophilic Esophagitis 01/2019 - 12/2012

Drug/Important Bio-Agent (IBA)

33	AcidsIBA 06/2022 - 08/2002
14	Proton Pump InhibitorsIBA 01/2022 - 08/2004
14	prucaloprideIBA 01/2021 - 08/2009
13	Pharmaceutical PreparationsIBA 07/2016 - 04/2006
12	Opioid Analgesics (Opioids)IBA 01/2022 - 10/2013
7	salicylhydroxamic acid (SHAM)IBA 11/2022 - 05/2007
7	Serotonin (5 Hydroxytryptamine)IBA 01/2019 - 01/2007
7	Neurotransmitter Agents (Neurotransmitter)IBA 01/2019 - 11/2005
7	Z 338IBA 01/2019 - 03/2011
6	tegaserod (Zelnorm)FDA Link 10/2022 - 08/2002
6	Proteins (Proteins, Gene)FDA Link 01/2022 - 02/2014
6	Bile Acids and Salts (Bile Acids)IBA 11/2021 - 02/2010
6	Botulinum Toxins (Botulinum Toxin)IBA 01/2020 - 09/2009
5	naloxegolIBA 02/2022 - 06/2014
5	Somatostatin (Somatotropin Release-Inhibiting Factor)IBA 01/2020 - 04/2009
5	Tricyclic Antidepressive Agents (Tricyclic Antidepressants)IBA 03/2018 - 01/2007
5	Antidepressive Agents (Antidepressants)IBA 03/2018 - 02/2009
4	Glucose (Dextrose)FDA LinkGeneric 01/2022 - 01/2019
4	AerosolsIBA 01/2022 - 01/2020
4	LipidsIBA 01/2021 - 01/2008
4	Parasympatholytics (Antispasmodics)IBA 01/2021 - 03/2013
4	5-HT4 Serotonin ReceptorsIBA 01/2021 - 08/2009
4	GhrelinIBA 01/2019 - 01/2014
4	eluxadolineIBA 10/2018 - 01/2016
4	linaclotideIBA 10/2018 - 02/2013
4	LaxativesIBA 10/2015 - 05/2009
3	goblet cell silencer inhibitorIBA 11/2022 - 05/2004
3	Capsules (Microcapsules)IBA 06/2022 - 11/2010
3	naldemedineIBA 01/2022 - 01/2021
3	octanoic acid (caprylic acid)IBA 01/2022 - 09/2007
3	Phenobarbital (Luminal)FDA Link 12/2021 - 11/2018
3	Anti-Bacterial Agents (Antibiotics)IBA 10/2021 - 07/2007
3	MotilinIBA 01/2021 - 01/2010
3	Peptides (Polypeptides)IBA 01/2020 - 01/2015
3	relamorelinIBA 12/2018 - 11/2017
3	Lubiprostone FDA Link 10/2018 - 05/2014
3	Buspirone (Buspar)FDA LinkGeneric 03/2018 - 11/2012
3	Mirtazapine (Rexer)FDA LinkGeneric 11/2017 - 02/2009
3	octylonium (otilonium bromide)IBA 03/2017 - 03/2013
2	Serotonin Receptor Agonists (Serotonin Receptor Agonist)IBA 01/2022 - 01/2020
2	BariumIBA 01/2022 - 09/2007
2	Baclofen FDA LinkGeneric 01/2022 - 01/2018
2	Hormones (Hormone)IBA 01/2022 - 01/2019
2	Fructans (Levans)IBA 01/2022 - 01/2020
2	itoprideIBA 01/2022 - 01/2019
2	Biomarkers (Surrogate Marker)IBA 01/2021 - 04/2006
2	Plant ExtractsIBA 01/2021 - 04/2020
2	Histamine (Histamine Dihydrochloride)FDA Link 06/2020 - 10/2019
2	Acarbose FDA LinkGeneric 01/2020 - 10/2009
2	lanreotide (Somatuline)FDA Link 10/2019 - 08/2016
2	Cholinesterase Inhibitors (Anticholinesterases)IBA 01/2019 - 06/2012
2	Budesonide (Pulmicort)FDA LinkGeneric 01/2019 - 03/2016
2	Adrenergic Agents (Adrenergic Drugs)IBA 01/2019 - 09/2014

Therapy/Procedure

45	Therapeutics 01/2022 - 10/2002
5	Drug Therapy (Chemotherapy) 01/2021 - 01/2007
5	Heller Myotomy 05/2016 - 01/2010
4	Gastrectomy 01/2021 - 09/2009
4	Bariatric Surgery 01/2021 - 10/2009
4	Myotomy 01/2020 - 11/2017
3	Enteral Nutrition (Feeding, Tube) 01/2022 - 10/2009
3	Fundoplication 01/2022 - 05/2011
3	Lasers (Laser) 01/2022 - 01/2021
3	Catheters 10/2020 - 01/2015
3	Gastric Balloon 01/2017 - 05/2007
2	Gastric Bypass (Roux-en-Y Gastric Bypass) 01/2021 - 08/2014
2	Nutritional Support (Artificial Feeding) 01/2021 - 01/2021
2	Conservative Treatment 01/2020 - 02/2012
2	Injections 01/2020 - 09/2013